Strategies to combat antimicrobial resistance: anti-plasmid and plasmid curing
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چکیده
منابع مشابه
Plasmid Curing Activity of Five Plant Extracts on Multiple Resistant Plasmid Bearing Klebsiella Pnumoniae Strains
ABSTRACT The curing of five medicinal plant extracts (Satureia hortensis, Glycyrrhiza glabra, Teucrium Pollium, Myrtus Communis, Eukalypetus globolus) on plasmid bearing strains of klebsilla pnenmoniae resistance to multiple antibiotics were investigated. Alcoholic and maceration extraction were carried out from leaves, fruits or roots of the above plants. Mimimum inhibitory concentrations (MI...
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Infectious diseases form the major health-care burden for the developing world and antimicrobials prove to be the magical drugs to combat this. The discovery of antimicrobial agents was boon for the global health-care system and the wonderful cure by antimicrobials shifted the disease trends from infectious to life-style diseases in the developed world. Sudden appearance of the antimicrobial re...
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Plasmids are extrachromosomal pieces of double-stranded circular DNA which have the capability to replicate independently of the.Growth dynamics of multiple component communities of bacteria. Thus curing by acridines normally involves loss of the whole plasmid.Plasmids are extrachromasomally replicating molecules of DNA present in bacteria.Plasmid curing is a process of completely removing plas...
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The selective pressure imposed by the use of antimicrobials in both human and veterinary medicine promotes the spread of multiple antimicrobial resistance. The dissemination of antimicrobial resistance in Salmonella enterica strains, causing severe enteritis in human, has been reported worldwide and is largely attributed to conjugative DNA exchange. In the present review, the relevance of plasm...
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The large plasmid pXO1 encoding the anthrax toxin is important for the virulence of Bacillus anthracis. It is essential to cure pXO1 from B. anthracis to evaluate its role in the pathogenesis of anthrax infection. Because conventional methods for curing plasmids (e.g., curing agents or growth at elevated temperatures) can induce mutations in the host chromosomal DNA, we developed a specific and...
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ژورنال
عنوان ژورنال: FEMS Microbiology Reviews
سال: 2018
ISSN: 1574-6976
DOI: 10.1093/femsre/fuy031